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Retatrutide goes further by simultaneously engaging three receptor systems

However, the absence of any signal across large-scale studies and the current pharmacovigilance data provides reasonable confidence that tirzepatide does not directly cause erectile dysfunction through its pharmacological mechanism

Mar 5 2024;465:133412

Scirica BM, Bhatt DL, Braunwald E, Steg PG, Davidson J, Hirshberg B, Ohman P, Frederich R, Wiviott SD, Hoffman EB, Cavender MA, Udell JA, Desai NR, Mosenzon O, McGuire DK, Ray KK, Leiter LA, Raz I, Committee S-TS, and Investigators

Recommended Assessment Tools Body Composition Analysis (Gold Standard): DEXA (Dual-Energy X-ray Absorptiometry) scanning provides precise body fat percentage, lean mass, and visceral fat measurements