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In SURMOUNT 1, tirzepatide induced a mean BW reduction of 15.0%, 19.5% and 20.9% with 5 mg, 10 mg and 15 mg, respectively compared to 3.1% obtained with placebo at 72 weeks 34
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However, more investigations are warranted to expand their applications to meet the evolving dermatological challenges
Worse yet, a 2024 study suggests that TB-500 itself may not even be the active compound, but that its healing activity might come from a smaller piece it breaks down into in the body
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