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Additionally, GLP-1 RAs exhibit neuroprotective and anti-inflammatory effects, increase Akt dephosphorylation, decrease proinflammatory factors such as TNF-, elevate neurotrophic factors like BDNF, reduce oxidative stress and microglial activation, and enhance gut-brain axis function and gut microbiota stability [176]
Formulation: Tirzepatide 10 mg/mL + Levocarnitine 100 mg/mL Schedule: Same titration as Protocol 1, with an additional oral L-carnitine supplement (500 to 1,000 mg, taken 60 to 90 minutes before exercise sessions) to boost total carnitine availability on training days
(2025) 6:e70116
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