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When T2D-like disease model mice are fed a high-calorie diet, the accumulation of oxidative stress in adipose tissue and senescence-associated alterations, including increases in p53 levels, proinflammatory cytokine levels, and senescence-associated beta-galactosidase activity, are observed
One study found that vitamin C plays an important role in restoring depleted glutathione levels (4)
doi: 10.1002/eji.201747024 195 BrandiPConejeroLCuetoFJMartnez-CanoSDunphyGGmezMJet al
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