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This "research use only" designation carries specific implications: Researchers are expected to use the material in legitimate research contexts, whether academic studies, independent investigation, or institutional research programs

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When morphology is similar across embryos but time-lapse rankings diverge, or when morphokinetic patterns are difficult to interpret under a given laboratory protocol, non-invasive spent-media molecular profiles can contribute information on metabolic efficiency and stress response that is not redundant with imaging, enabling more transparent multimodal prioritisation within a cohort [476, 478]

Several factorsfrom dosing schedules and biological differences to lifestyle habits and concurrent medicationscan influence how well these treatments work

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