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In contrast with P478L, this second mutation abrogates both carnitine and organic cations transport

Later stage

Tirzepatide Outcomes (SURMOUNT-1) The SURMOUNT-1 randomized clinical trial evaluated tirzepatide at three dose levels: 5 mg, 10 mg, and 15 mg weekly in adults with obesity

[8] Liraglutide (Saxenda) also licensed for weight management in adults meeting similar BMI thresholds

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