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[18] Cyanocobalamin is the most common form used in dietary supplements and food fortification because cyanide stabilizes the molecule against degradation

The body requires enough time to absorb sufficient supplement levels from oral sources, particularly when the deficiency reaches severe levels

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In the UK, cyanocobalamin is commonly used for oral supplementation due to its stability and effectiveness, whilst hydroxocobalamin injections are the preferred treatment for confirmed deficiency, particularly in pernicious anaemia or malabsorption conditions

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