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The increased and/or decreased expression of AOX along with the inhibition of its activity, have been considered as important factors in the establishment of the mitochondrial generation of ROS in signal transduction pathways (Vishwakarma et al., 2015) with the induction of AOX described as a mitochondrial retrograde signaling model (Maxwell et al., 1999

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In the EU, IPBC concentration limits are set at 0.02% in rinse-off products and 0.01% in leave-on products

doi: 10.1053/meta.2001.24192