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While the studies reviewed above highlight the importance of both iron import and storage to strongly advocate for targeting ferritin as a strategy to eliminate CSCs, a few studies advise caution in pursuing this approach
Ethylmercury has a shorter half-life and greater difficulty crossing the blood brain barrier than methylmercury [Citation84]
& Peersen, O
Because angiogenesis is a defining hallmark of tumor growth and metastatic progression, any therapeutic agent that enhances neovascularization could, in theory, facilitate tumor expansion and promote metastatic dissemination
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