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doi: 10.1055/s-0031-1271777 49 Ben NasrMUsuelliVDellepianeSSeelamAJFiorentinoTVDAddioFet al

However, this result is expected considering the very high activity of glutaredoxins as deglutathionylating enzymes and a decreased GSSR concentration neither excludes mechanism (ii) or (iii) from Fig

it is continuously recycled back into its active state

FIGURE 2 Investigating ferroptosis not only expands our knowledge of the intricate mechanisms underlying migraines, but it also creates new opportunities for locating possible targets for treatment

Differences in cancer outcome definitions across trials were addressed by grouping clinically equivalent endpoints (e.g., hepatocellular carcinoma and primary liver cancer) and accounting for heterogeneity through random-effects modeling, sensitivity analyses, and GRADE downgrading for indirectness where appropriate