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Ethics declarations Ethics approval and consent to participate The research was approved by the Royal Adelaide Hospital Human Ethics Committee (RAH protocols #060903 and #140201)
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Epithalon induces decondensation of heterochromatin, particularly pericentromeric structural heterochromatin, releasing genes that become repressed due to age-related chromatin condensation
Its potential molecular features include elevated urinary ferritin, increased ACSL4 expression, reduced GPX4 levels, increased MDA and ROS, and activation of ALOX15 and HMOX1 (Wu et al., 2023
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