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The model of impaired glucose tolerance (IGT) mice was established by a one-week injection of streptozotocin

Human clinical trials remain sparse

Many longevity practitioners evaluate biological age through: Body composition Blood biomarkers Inflammatory markers Metabolic health Epigenetic testing Functional performance Epitalon is being explored as a tool that may support a younger biological profile by targeting cellular aging mechanisms

Saxenda (liraglutide): FDA approved this for obesity, but it does not work as well as some of the newer treatments

Avoid in patients with renal disease, corn allergy, or G6PD mutation