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The drug tested was called Lixisenatide, which is a glucagon-like peptide-1 receptor agonist, designed primarily for use in diabetes

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Caffeines link to metabolism is well established: caffeine elevates the metabolic rate by stimulating the central nervous system, increasing catecholamine release, and promoting lipolysis, the breakdown of stored fat into free fatty acids available for oxidation

doi:10.1371/journal.pone.0009390

doi: 10.1056/NEJMoa0802743 15 CrabtreeTOgendoJ-JVinogradovaYGordonJIdrisI