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This research explores a novel therapeutic avenue by targeting the brains renin-angiotensin system (RAS) and its interaction with the hepatocyte growth factor (HGF)/c-Met receptor system [2]

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Gastroenterology 135:100110 Ratziu V, Charlotte F, Bernhardt C et al (2010) Long-term efficacy of rosiglitazone in nonalcoholic steatohepatitis: results of the fatty liver improvement by rosiglitazone therapy (FLIRT 2) extension trial

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Circadian rhythm restoration and melatonin regulation This is the mechanism most immediately noticeable to patients

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