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The role of glucocorticoids in inflammatory diseases

Capcarova M, Petruska P, Zbynovska K, Kolesarova A, Sirotkin AV

Vitamin C can cause a brief purging phase, although its less common compared to stronger actives like retinoids

In addition, the cycle can produce NADPH in addition to NADH, due to the activity of isozymes that reside either in the mitochondria (isocitrate dehydrogenase 2/IDH2) or cytosol (IDH1 or malic enzyme/ME1) (Rydstrom, 2006)