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181 , R211R234 (2019)
Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes
While these medications can be highly effective for many people, research shows that approximately 10-15% of patients experience minimal or no weight loss, even when following their prescribed regimen
However, it has shown remarkable efficacy in promoting weight loss
Therefore, targeting the mtROS-p38 MAPK (Thr180/Tyr182) axis represents a promising strategy
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