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Conventional treatments, such as Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), often fail because they target inflammation, which is largely absent in chronic tendinosis

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Strict vegans and vegetarians are also at higher risk for deficiency since B12 occurs naturally only in animal-derived foods

PubMed laboratory research record [PMID: 4382748] PubMed record related to this compound for laboratory literature review

It requires a needle, which may lead to anxiety or discomfort, especially for individuals with a fear of needles