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The needle is fine, and the injection site is only slightly tender for a short time afterwards in some cases

Vitamin B12 is essential for neurologic function, red blood cell creation, and DNA synthesis and is a coenzyme for three primary biochemical conversions: homocysteine to methionine, 5-methyltetrahydrofolate to tetrahydrofolate, and methylmalonic acid to succinyl coenzyme A [1, 2]

If neurological symptoms were present at diagnosis, your doctor may perform a neurological examination at follow-up appointments to assess improvement

It also avoids the pain and cost of repeated clinic visits

Yes, and in fact, some research designs do exactly that to separate endocrine-mediated effects from direct fat cell effects in the same experimental system