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Given their popularity and the results that are being seen with their use, that is a question that is unlikely to get answered in a satisfactory way anytime soon and should be left to the individual and their prescribing physician.

They An example of a short-acting GLP-1 RA approved for use in the United States is exenatide, which is injected subcutaneously within 60 minutes prior to morning and evening meals (or before the two main meals of the day, approximately 6 or more hours apart)
This brings us, you mentioned about the Parkinson's, and when I reviewed the three randomized Parkinson's trials, they're all small, but it appears to be the first disease modifying drug ever in Parkinson's

An unexpected but exciting side effect of this medication was weight loss

Int J Obes (lond)
