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Mechanistic experiments using the PI3K inhibitor wortmannin demonstrated that PI3K/AKT signaling is required for the anti-inflammatory and anti-apoptotic effects, identifying the brain AngIV/PI3K/AKT axis as the proximate mechanism in this model

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Reconstitution Guidelines Use bacteriostatic water or sterile water for reconstitution Add solvent slowly along the vial wall do not shake Gently swirl until fully dissolved (clear solution) Store reconstituted solution at 2-8C and use within 28 days Use sterile technique throughout to prevent contamination HPLC Verified 98% purity certified Australian Owned Local team, local support Discreet Shipping Plain packaging AU-wide Research Grade Lab-quality peptides

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Alkali-Burn Wound Healing, VEGF-A & ERK1/2 (PMC / Dove Press, 2015) A controlled study published in PMC and Dove Press investigated BPC-157s effects on alkali-burn wound healing in vivo and on HUVEC (human umbilical vein endothelial cell) behaviour in vitro

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