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The liver is especially relevant because it produces and uses large amounts of SAM, manages homocysteine through both remethylation and transsulfuration, synthesizes glutathione and carries out methylation- dependent reactions
Immunol Lett (2001) 76:1338
Nevertheless, in contrast to the vast knowledge collected about the detoxification function of GSTs, the understanding of their role in endogenous plant processes and about their metabolic substrates had been still far from complete (Marrs, 1996
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