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This is the central tension of training on a GLP-1 drug, and managing it well is the difference between losing fat while preserving muscle and losing both

The Phase 1 head-to-head will be the first read on whether the mouse weight-loss gap and the primate half-life translate

Other GLP-1 and glucagon co-agonists in early phase clinical trials as treatments for obesity include AZD9550 and LY3305677 (NCT05623839)

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