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Liraglutide significantly reduced lipid deposition and increased vascular smooth muscle cell and collagen content in plaques, thus enhancing plaque stability

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The mean change in body weight from baseline to week 104 was -15.2% in the semaglutide group (n = 152) versus -2.6% with placebo (n = 152), for an estimated treatment difference of -12.6 %-points (95% confidence interval, -15.3 to -9.8

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