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The mc2r gene, which is expressed in the adrenal gland and is involved in adrenal biosynthesis, has also been linked to pigmentation

FDA labels note that dehydration from gastrointestinal adverse effects can contribute to acute kidney injury in some cases

Flavonoids are a broad group of secondary metabolites, recognized to possess a diverse range of biological activities, including antioxidant, anti-inflammatory, anti-diabetic and diabetes-related complications like diabetic neuropathy, anti-microbial, anti-cancer, neuroprotective, and cardioprotective-properties (Panche et al