APAP administration increases ROS in the drosophila fat body and depletes systemic glutathione In the mammalian liver, APAP is bio-converted into the toxic metabolite NAPQI by the Cytochrome P450 enzyme CYP2E1 4
doi: 10.1016/j.ebiom.2018.06.005 Summary Keywords tubular injury, diabetic kidney disease, mechanism, therapy, programmed cell death, stem cell Citation Wang Y, Jin M, Cheng CK and Li Q (2023) Tubular injury in diabetic kidney disease: molecular mechanisms and potential therapeutic perspectives
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