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Glutamate functions as a crucial energy substrate for enterocytes, where amino acid absorption and glucose metabolism occur predominantly 9

N -Methyl-D-aspartic acid (NMDA) is -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) were blocked by 10 M (RS)-CPP (Tocris) and 10 M NBQX (Tocris), respectively

Our bodies naturally decrease in NAD+, with up to 65% decline between ages 30-70

Adding the 9mg arm suggests the sponsor believes the 8mg to 12mg range contains the optimal therapeutic dose and wants more granular data to identify it precisely

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