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As two independent reviewers searched the electronic PubMed/MEDLINE, Scielo, Embase and Lilacs databases using the either the Medical Subject Headings (MeSH) terms or keywords semaglutide or GLP-1RA, combined with inflammation or C-reactive protein (CRP) or cytokines, or using the term semaglutide with the randomised clinical trials filter, and the data were extracted

This makes it challenging to separate drug effects from underlying disease risk in research studies

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