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Extrinsic aging is predominantly influenced by sun exposure (photoaging), although smoking and pollution also play a role.1 Intrinsic and extrinsic aging overlap in clinical practice.1 Demand for strategies to mitigate the signs of skin aging is high.2 Recent studies suggest that regular exercise, apart from improving quality of life and reducing the risk of mortality and chronic disease,2 might also reduce the thickness of the stratum corneum and improve dermal thickness and collagen content.3 Diet is also important, with a number of studies highlighting its role in the prevention of aging
Retrieved from Wolraich, M., Brown, L., Brown, R
Protocol Details Testosterone therapy continues per the patients established protocol
Research Evidence Comparison# CagriSema Research# The REDEFINE Phase 3 program provides robust evidence: REDEFINE 1 (3,417 participants, 20.4% weight loss at 68 weeks) and REDEFINE 2 (1,200 T2D participants, 13.7% weight loss)
Onset and adaptation: Appetite suppression effects appear within weeks, though side effects (nausea, fullness) may be stronger during dose escalation
