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It results from blood sugar fluctuations, dehydration from GI symptoms, and in some cases, blood pressure changes
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If there is ever uncertainty about how long a pen has been unrefrigerated or whether it exceeded temperature limits, it is safer to discard the pen and start a new one rather than risk reduced effectiveness or safety concerns
It affects 1 in 3 adults
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It belongs to a class of drugs called GLP-1 receptor agonists, which help lower blood sugar by increasing insulin release, decreasing glucagon secretion, and slowing gastric emptying
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