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A number of clinical observations suggest that Down patients may have a functional folate deficiency despite having normal plasma levels of folate and vitamin B 12 [13]
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Every patient should be aware of the following warning signs, which require prompt medical evaluation: Severe, persistent abdominal pain especially pain that radiates to the back can be a sign of pancreatitis
The serious side effects are a dosing problem masquerading as a drug problem
Diabetologia 50:11481155 Fonseca V, Baron M, Shao Q, Dejager S (2008) Sustained efficacy and reduced hypoglycemia during one year of treatment with vildagliptin added to insulin in patients with type 2 diabetes mellitus
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