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Beyond macronutrients, the interaction between caloric restriction and micronutrient deficiencies is another key mechanism driving bone loss during weight reduction
As we did not observe any discontinuation of treatment during the study period, it remains unclear whether pwIIH successfully treated with GLP-1-RAs sustain their weight loss, or a yo-yo effect occurs [44], which would pose an increased risk for a disease relapse
This indication is currently under FDA review
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