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Sodium-glucose cotransporter 2 (SGLT2) inhibitors have demonstrated both kidney- and heart-protective effects in individuals with CKD, and other agents, such as non-steroidal mineralocorticoid receptor antagonists (ns-MRA), provide cardio-kidney protection in patients with diabetes and kidney disease

doi: 10.1042/BSR20171284 213 RobinsonALubitzIAtrakchi-BaranesDLicht-MuravaAKatselPLeroithDet al

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Thomas MK, Nikooienejad A, Bray R et al (2021) Dual GIP and GLP-1 receptor agonist tirzepatide improves beta-cell function and insulin sensitivity in type 2 diabetes