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In DKD, upregulation of local angiotensin II in the renal tubule, activation of vascular endothelial growth factor (VEGF), and reduction of nitric oxide (NO) (60) can lead to constriction of both the afferent and efferent arterioles, as well as the interlobular arteries, compromising blood flow regulation

In HR+ and HER2+ breast cancers, ML models have established the ability to correctly classify patients for CDK4/6, HER2, and PI3K pathway inhibitors, which is beneficial for precision oncology (255)

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However, these case reports are often authored by individuals who have a vested interest in promoting peptides