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It is not blocking a pathway, it is speeding up a repair that would otherwise take much longer or stall entirely

Torres-Rosado A, OShea KS, Tsuji A, Chou SH, Kurachi K

Figure 3 In another study comparing the neuroprotective effects of two other novel GLP-1/GIP dual receptor agonists (DA-JC4, DA-CH5) with the GLP-1 single receptor agonist liraglutide and the first-generation GLP-1/GIP dual receptor agonist DA-JC1 in MPTP-induced PD mice, the results concluded that the new dual receptor agonists have clear neuroprotective effects (112)

doi: 10.1007/s00296-016-3481-8 95 BinduSMazumderSBandyopadhyayU

Whether these distinct forms of cell death related to distinct pathologies, CNS regions, age, or subpopulations of OLs remains to be defined