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Tirzepatide is a synthetic compound derived from gastric inhibitory polypeptide (GIP), with the added functionality of glucagon-like peptide-1 (GLP-1)
BPC 157 treatment led to the upregulation of Egr1, Akt1, Kras, Src, Foxo, Srf, Vegfr2, Nos3, and Nos1 and the downregulation of Nos2 and Nfkb compared with untreated rats
Some semaglutide formulations also have both B6 and B12 to help relieve side effects, such as nausea, or prevent lethargy and fatigue in patients taking GLP-1 drugs for weight loss or type 2 diabetes