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Its extreme local potency, coupled with the systemic risks inherent to IGF-1 (such as potential tumor acceleration and long-term changes in glucose regulation), means its use should be strictly confined to controlled research settings with rigorous safety monitoring
It produces what researchers call "biased signaling" at the GLP-1 receptor, resulting in less receptor desensitization over time
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But in some cases, this slowing becomes excessive, leading to food sitting in the stomach for hours longer than normal, causing severe bloating, pain, and vomiting of undigested food
Los ensayos clnicos continan para evaluar su seguridad y eficacia a largo plazo
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