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Recent findings have shown that lysosomal cholesterol accumulation exacerbates APAP-induced hepatotoxicity and liver injury by impairing mitophagy without increasing APAP metabolism or NAPQI generation ( Figure 4 )
Tumor necrosis factor-alpha mediates oligodendrocyte death and delayed retinal ganglion cell loss in a mouse model of glaucoma
Timelines vary based on the condition being treated
Barry Conrad That's so interesting
Eur J Clin Invest 22: 283-291, 1992
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