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As superoxide is subject to efficient dismutation by cellular superoxide dismutases, it is possible that NFT might directly interact with Keap1 to induce the observed release of Nrf2 and its escape from proteasomal degradation

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Schnichels, S., Paquet-Durand, F., Loscher, M., Tsai, T., Hurst, J., Joachim, S

While the magnitude of this effect varies among individuals, even modest increases in metabolic rate can support sustained fat loss over time