The paradigm for treating people with obesity has often been to recommend lifestyle changes, and then if they develop diabetes or another metabolic condition, to treat them with metformin, insulin, or GLP-1 drugs, Andrew Stokes, senior author and associate professor of global health at Boston University
They work by mimicking the action of the GLP-1 hormone, which regulates blood sugar levels, suppresses appetite, and promotes a feeling of fullness, making it easier to reduce calorie intake
Rangwala SM, DAquino K, Zhang YM, Bader L, Edwards W, Zheng S, et al
This dual action not only improves blood sugar levels but also holds promise in fostering significant weight loss
Previous Depo-Provera Lawsuit Updates Depo-Provera Litigation Updates From 2024 & 2025 December 17, 2025: Pfizer Updates Depo-Proveras Label to Include Risk of Brain Tumors On December 12, 2025, the FDA notified Pfizer that it had approved updates to Depo-Proveras warning label to include an increased risk of meningiomas