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4.3 Modulation of SCFAs-producing bacteria by metformin SCFAs (such as acetic acid, propionic acid and butyric acid) are usually metabolites produced by various SCFAs-producing bacteria in the gut that metabolizes carbohydrates such as dietary fiber (Rau et al., 2018), and they are essential for the health of the gut, the body and even the brain

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The two main incretin hormones in humans are GLP-1 and GIP