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Accordingly, an aspect of the present invention relates to a cation exchange chromatography process for purifying a GLP-1 peptide from a mixture comprising said peptide and related impurities, comprising the step of: separating said GLP-1 peptide and said related impurities of said mixture by elution in a solution comprising an organic modifier, water, optionally a salt component, and optionally a buffer, with a linear or step gradient or isocratically in salt component and/or with a linear or step pH-gradient or at a constant pH-value, wherein the pH-gradient or pH-value should be in the range where said peptide has a positive local or overall net charge different from the local or overall positive net charge of said related impurities so as to remove said related impurities

Ipamorelin literature fits into that broader GHSR research context

Understanding what these individual compounds doand more importantly, what they dont doreveals the fundamental problem with GLP-1 booster marketing: the disconnect between what the science shows and what consumers are led to believe