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Bibcode:2020Sci...369.1490K
This protective effect is mediated through the upregulation of GPX4, a key regulator of ferroptosis that mitigates lipid peroxidation and cellular damage
It is also used in glutamate-cysteine ligase regulation and Nrf2/ARE pathway work, where glutathione acts as the feedback inhibitor of its own synthesis (Lu, Biochimica et Biophysica Acta, 2013)
GLP-1 (Glucagon-Like Peptide-1) is a natural hormone produced in the gut
An extended insertion known as the receptor-binding motif (RBM) from the core contains two short strands, two helices, and loops
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