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A growing body of evidence is studying the relationship between neurodegenerative diseases such as PD and type 2 diabetes mellitus (T2DM)

Ive really only mentioned the biggest con of GLP-1 agonists which is a potential risk of thyroid cancer but there are others to consider such as muscle loss as well

FDA's April 1 update explicitly confirms that neither semaglutide nor tirzepatide currently appears on either list

Another difference: PDE5is (especially sildenafil) have interactions (e.g., with high-fat meals delaying absorption, with nitrates causing hypotension)

However, the role of GCG in WAT has not been thoroughly investigated