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Over the following decades, studies looked at its role in collagen and elastin support, wound healing, antioxidant activity, inflammatory signaling, and the production of glycosaminoglycans that help keep skin hydrated and firm

2 Diuretics: brief historic perspectives 2.1 Thiazides and thiazide-like diuretics Hydrochlorothiazide and chlorthalidone, a benzothiadiazide and a thiazide-like diuretic, respectively were introduced during 1957-59 and the former quickly became a mainstay in the treatment of hypertension

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