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[3] However, these studies were not designed to assess rheumatoid arthritis-specific outcomes such as joint pain, swelling, Disease Activity Score (DAS28), or radiographic progression

One animal study reported that following the administration of acetyl L-carnitine to Wistar rats, the serum levels of TC, TG, Low-Density Lipoprotein (LDL), and Very Low-Density Lipoprotein (VLDL) in the L-carnitine group were significantly reduced compared to the atherosclerosis group, while the level of HDL was markedly elevated (Wang et al

A landmark 2011 study by Chang et al

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