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RETA also improved systemic metabolism in LLC model with a significant reduction in fasted blood glucose concentrations 1 week after starting the treatment continuing until endpoint where glucose concentrations were 41% lower compared to Veh (Fig
The clinical implications of this are profound
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That is, for each participant, GSH levels were estimated after correcting for partial volume effects in each voxel using the method proposed in Gasparovic et al(Gasparovic et al., 2018), and GABA levels were alpha-corrected(Harris et al., 2015), since metabolite levels are reported to differ between brain gray and white matter(Gong et al., 2022)
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