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It is described as a triple hormone receptor agonist, meaning it activates: GLP-1 receptors GIP receptors Glucagon receptors This differentiates it from currently approved therapies such as: Wegovy (GLP-1 only) Mounjaro (GLP-1 + GIP) Retatrutide adds glucagon receptor activation, creating a triple-pathway metabolic effect
doi:10.3390/nu11092073
Res Sq2026 May 21
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