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Proteins were ranked using a composite weighting metric calculated as log10(FDR) |log2 fold change|, where FDR represents the BenjaminiHochberg adjusted p-value and log2 fold change represents the abundance difference between groups

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Independent analytical testing and supporting laboratory documentation are available where applicable to assist with product verification and batch traceability

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Additional treatments, such as the Pan-PPAR agonist bezafibrate and the AMPK agonist AICAR, have shown the potential to partially restore COX function in human and animal models (106)