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The findings don't all point in the same direction with equal strength, but certain patterns have appeared repeatedly across independent research groups
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M.Abou-SleimanP
Within the brain, DSIP is particularly abundant in the hypothalamus, hippocampus, and limbic regions, where it interacts with multiple peptide and non-peptide mediators, including corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), and melanin-concentrating hormone (MCH)
Localized (intra-articular) injection delivers the compound directly into the joint
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