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Side effects track dose increases, not the absolute dose, and they improve on a stable dose
Also, an increased incidence of hypoglycemia and elevated blood fats was observed
For instance, as appetite is suppressed, patients may inadvertently consume fewer fluids or miss out on essential nutrients, both of which can lead to dehydration and subsequent headaches
But GLP-1 was quickly chewed up in the blood by enzymes, and giving diabetic participants large doses of it made them throw up
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